厚皮马拉色菌感染引起1名养狗者皮肤肉芽肿  

Granulomatous skin infection caused by Malassezia pachydermatis in a dog owner

作　　者：潘敏 

出　　处：《世界核心医学期刊文摘（皮肤病学分册）》2006年第12期60-60,共1页Digest of the World Core Medical JOurnals:Dermatology

摘　　要：Background: Malassezia pachydermatis is part of the normal cutaneous microflora of dogs and many other mammals. M pachydermatis has not yet been reported as an agent that causes skin infection in humans, although it has been found to cause fungemia and other nosocomial infections in preterm newborns and immunocompromised adults. Observations: Malassezia pachydermatis was isolated from the facial granuloma of a healthy woman and her dog’s skin scrapings and cerumen. The yeast identity was established by standard methods and scanning electronmicroscopy. A skin biopsy specimen showed chronic inflammatory granuloma, numerous purple-red round or ovoid spores in the superficial necrotic tissue, and sparse red spores in the dermis. The skin lesions healed after oral fluconazole and cryotherapy. Conclusions: Definite diagnosis of M pachydermatis -induced skin infection principally depends on the results of fungal culture and histologic examination, and the combination of oral fluconazole and adjunctive cryotherapy seems to be an effective therapeutic regimen.Background: Malassezia pachydermatis is part of the normal cutaneous microflora of dogs and many other mammals. M pachydermatis has not yet been reported as an agent that causes skin infection in humans, although it has been found to cause fungemia and other nosocomial infections in preterm newborns and immunocompromised adults. Observations: Malassezia pachydermatis was isolated from the facial granuloma of a healthy woman and her dog s skin scrapings and cerumen. The yeast identity was established by stan...

关 键 词：厚皮马拉色菌 肉芽肿 炎症 氟康唑 冷冻治疗 

分 类 号：R756[医药卫生—皮肤病学与性病学]