皮肤肥大细胞增生病:55例患者的病谱及临床特征  

Cutaneous mastocytosis:Demographic aspects and clinical features of 55 patients

作　　者：Akoglu G. Erkin G. Cakir B. 董平 

机构地区：[1]Hacettepe University, Faculty of Medicine, Department of Dermatology, P.O. 06100, Sihhiye,Ankara, Turkey

出　　处：《世界核心医学期刊文摘（皮肤病学分册）》2006年第12期34-34,共1页Digest of the World Core Medical JOurnals:Dermatology

摘　　要：Background: Mastocytosis is a rare, heterogeneous group of disorder with abnormal increase of mast cells in one or more organ systems. Objective: To evaluate the demographic and clinical features of cutaneous mastocytosis (CM). Methods: Records of 55 patients with cutaneous mastocytosis were retrospectively analysed. Results: Of the 22 females and 33 males, 80%had urticaria pigmentosa/ maculopapular CM and 20%had mastocytoma. Of all cases, 81.8%had first lesions in childhood. The most common presentation was involvement of trunk together with extremities. Thirteen (23.6%) patients had history of bulla; Darier’s sign was positive in 34 of 38 patients. Itching was the most common complaint, provocated by hot weather/bath. Conclusion: Clinical presentations of urticaria pigmentosa/maculopapular CM and mastocytoma are similar regarding gender, age of onset, age of diagnosis, and presence of Darier’s sign and history of bulla. In contrast to mastocytoma, urticaria pigmentosa/maculopapular CM lesions were frequently located on trunk together with extremities.Background: Mastocytosis is a rare, heterogeneous group of disorder with abnormal increase of mast cells in one or more organ systems. Objective: To evaluate the demographic and clinical features of cutaneous mastocytosis (CM). Methods: Records of 55 patients with cutaneous mastocytosis were retrospectively analysed. Results: Of the 22 females and 33 males, 80%had urticaria pigmentosa/ maculopapular CM and 20%had mastocytoma. Of all cases, 81.8%had first lesions in childhood. The most common presentation wa...

关 键 词：肥大细胞增生病 斑丘疹 色素性荨麻疹 患者 皮肤 解剖部位 临床特征 

分 类 号：R758.5[医药卫生—皮肤病学与性病学]