单侧痣样毛细血管扩张对脉冲染料激光的反应  

Unilateral nevoid telangiectasia:Response to pulsed dye laser

作　　者：Sharma V.K Khandpur S. 朱国兴 

机构地区：[1]Department of Dermatology and Venereology, All India Institute of Medical Sciences, NewDelhi-110029, India Dr.

出　　处：《世界核心医学期刊文摘（皮肤病学分册）》2006年第12期18-19,共2页Digest of the World Core Medical JOurnals:Dermatology

摘　　要：Background: Unilateral nevoid telangiectasia (UNT) is a unique vascular dermatosis of ambiguous etiology. The therapeutic role of pulsed dye laser in this condition, especially in individuals with skin types III and IV, has not been elucidated completely. The aim of this study was to assess the response to flash-lamp pulsed dye laser of UNT in Indian patients. Methods: A detailed analysis of nine confirmed cases of UNT patients was undertaken to determine the possible etiologic association of this disease. Six cases were treated with pulsed dye laser in combination with cryogen cooling using the following parameters: spot size, 7 mm; fluence, 5-7.5 J/cm2; wavelength, 585 nm; pulse duration, 450 μs. The procedure was repeated every 4-6 weeks and the response was assessed both clinically and photographically before each session. Results: The cases had a mean age of presentation of 20.6 years with an age of onset varying from 2.5 to 23 years. The lesions were located on the head and neck region in four patients, upper limb in four, and lower limb in one. No significant etiologic association could be established. Of the six cases treated with pulsed dye laser, a moderate response (26-50%lightening) was achieved in all cases after a mean of 2.33 sessions, a good response (51-75%lightening) was observed in four patients after 3.25 sessions, and an excellent response (> 75%lightening) was found in three patients after 3.66 sessions. Mild and reversible pigmentary alterations occurred in five cases, with mild textural change in one case. There was no scarring. No recurrence was observed. Conclusion: Pulsed dye laser is a useful modality for treating UNT in Indian patients. Reversible pigmentary changes are the major side-effects.Background: Unilateral nevoid telangiectasia (UNT) is a unique vascular dermatosis of ambiguous etiology. The therapeutic role of pulsed dye laser in this condition, especially in individuals with skin types III and IV, has not been elucidated completely. The aim of this study was to assess the response to flash-lamp pulsed dye laser of UNT in Indian patients. Methods: A detailed analysis of nine confirmed cases of UNT patients was undertaken to determine the possible etiologic association of this disease. ...

关 键 词：单侧痣样毛细血管扩张 脉冲染料激光 色素改变 反应 

分 类 号：R758.6[医药卫生—皮肤病学与性病学]