泌尿生殖医疗环境中临床诊断性活检的应用:新经验及文献回顾  

The usefulness of a diagnostic biopsy clinic in a genitourinary medicine setting:Recent experience and a review of the literature

作　　者：Palamaras I. Hamill M. Sethi G. 李政霄 

机构地区：[1]Department of Genitourinary Medicine, St. Mary's Hospital, Jefferiss Wing, London W2 1NY, United Kingdom

出　　处：《世界核心医学期刊文摘（皮肤病学分册）》2006年第12期27-27,共1页Digest of the World Core Medical JOurnals:Dermatology

摘　　要：Genital diseases include a wide range of lesions e.g. infectious and inflammatory. In most cases a clinical diagnosis is reached without the need for a biopsy. Nonetheless, a genital biopsy is safe and may help to confirm the diagnosis. We established a dedicated diagnostic biopsy clinic in 2003. Our objective was to evaluate the effectiveness of our diagnostic biopsy clinic and compare it with other Genitourinary medicine (GUM) clinics in the UK. A retrospective case-note study was performed on 71 patients referred to the biopsy clinic with persistent genital lesions over a 12-month period. Forty-seven biopsies were performed (71%biopsy rate). 43 specimens (92%) were appropriate for histopathological diagnosis. Of these 15%were lichen planus, 15%lichen sclerosis, 10%psoriasis, 7.5%each: eczema, Zoon’s and non-specific balanitis. The remainder represented a variety of other conditions. In 27 cases (68%) the clinical diagnosis was consistent with the histological result. The possibility of self-referral and walk-in nature of our GUM service substantially decrease the waiting times for assessment of anogenital disorders. We had a lower biopsy rate for the diagnosis of non-specific balanitis (7.5%) compared with the average rate (21.5%) in 14 UK GUM clinics and good agreement between clinical and histological diagnosis. An empirical first treatment, with simple emollients before biopsy, appears to be a safe clinical approach for the treatment of non-specific balanitis. A multidisciplinary approach (GUM physicians, dermatologists and urologists/gynaecologists) could help prevent unnecessary biopsies and improve correlation between clinical and histological diagnosis.Genital diseases include a wide range of lesions e.g. infectious and inflammatory. In most cases a clinical diagnosis is reached without the need for a biopsy. Nonetheless, a genital biopsy is safe and may help to confirm the diagnosis. We established a dedicated diagnostic biopsy clinic in 2003. Our objective was to evaluate the effectiveness of our diagnostic biopsy clinic and compare it with other Genitourinary medicine (GUM) clinics in the UK. A retrospective case-note study was performed on 71 patients...

关 键 词：泌尿生殖 诊断性 龟头炎 阴茎疾病 

分 类 号：R691[医药卫生—泌尿科学]