流感疫苗可触发大疱性类天疱疮?西班牙加利西亚的一项生态学研究  

Bullous pemphigoid triggered by influenza vaccination? Ecological study in Galicia,Spain

作　　者：Garca-Doval I. Mayo E. Nogueira Faria J. CrucesM.J. 周少娜 

机构地区：[1]Department of Dermatology, Complexo Hospitalario de Pontevedra, C/Loureiro Crespo 2, Pontevedra E-36000, Spain

出　　处：《世界核心医学期刊文摘（皮肤病学分册）》2006年第12期17-17,共1页Digest of the World Core Medical JOurnals:Dermatology

摘　　要：Background: Influenza vaccination has been suggested to be a trigger for bullous pemphigoid (BP). In our area most new patients with BP are admitted to hospital. Objectives: To detect a difference in the rate of admissions to hospital for BP during population influenza vaccination programmes, which are mainly targeted at individuals aged 65 years or older, start in the last week of September and last for 2 months. Methods: An ecological study in Galicia, north-west Spain (1997-2005), restricted to people aged 65 years or older. Using Poisson regression, results were controlled for mean age of admission and percentage of the population vaccinated each year. Results: There were 29 admissions registered during ‘vaccination periods’(i.e. approximately 10 weeks per year, including the period of vaccination and two further weeks), and 158 during nonvaccination periods (the rest of the year). The incidence rate ratio of admissions for BP in vaccination vs. nonvaccination periods was 0.85 (95%confidence interval 0.57-1.27, P = 0.43). Conclusions: Our data do not support the hypothesis of influenza vaccination being an important trigger for severe BP on a population level.Background: Influenza vaccination has been suggested to be a trigger for bullous pemphigoid (BP). In our area most new patients with BP are admitted to hospital. Objectives: To detect a difference in the rate of admissions to hospital for BP during population influenza vaccination programmes, which are mainly targeted at individuals aged 65 years or older, start in the last week of September and last for 2 months. Methods: An ecological study in Galicia, north-west Spain (1997-2005), restricted to people ag...

关 键 词：大疱性类天疱疮 流感疫苗 流感病毒疫苗 生态学研究 西班牙 南欧 

分 类 号：R758.66[医药卫生—皮肤病学与性病学]