我院抗菌药物消耗量统计与细菌耐药率分析  

Consumption of Antibiotics and Dynamic Analysis of Bacterial Resistance Rate

作　　者：郑晓林[1] 廖致红[1] 

机构地区：[1]广西医科大学第五附属医院,广西柳州545001

出　　处：《中国现代应用药学》2006年第S1期687-690,共4页Chinese Journal of Modern Applied Pharmacy

摘　　要：目的了解我院菌药物的使用状况及细菌耐药率的变化趋势,为临床合理使用抗菌药物提供依据。方法利用DDD数分析方法对我院2002年~2004年抗菌药物消耗量进行统计,并对同期细菌培养分离结果和药敏试验中各类抗菌药物的耐药率进行比较分析。结果2002年~2004年我院抗菌药物DDD s年平均增长率为6.51%,头孢菌素类、青霉素类、喹诺酮类和大环内酯类占抗菌药物DDD s78%以上,DDD s排序上升较快的是β-内酰胺?β-内酰胺酶抑制剂复合药和硝基咪唑类;3480株致病菌中敏感菌株1868株,占53.67%,耐药菌株1612株,占46.32%;耐药率较高的分别是青霉素类、大环内酯类、头孢菌素类和喹诺酮类,耐药率上升较快的是抗真菌药、β-内酰胺?β-内酰胺酶抑制剂复合药和喹诺酮类。结论抗菌治疗应参照药敏结果,结合临床疗效合理选用抗菌药物,控制抗菌药物用量,防止或减缓细菌耐药性产生。OBJECTIVE To learn the situation of antibiotic medicine used in our hospital and the trend of bacterial resistance rate in order to privide the evidence for rational application of clinical antibiotics.METHODS The consumption of antibiotic medicine of our hospital during 2002～2004 was investigated by the method of DDD system,and the resistance rate has gotten on conparative analysis with all kinds of antibiotics in medical sensible test within the same period.RESULTS The annual avrerage rate of growth of an...

关 键 词：抗菌药物 耐药率 药敏试验 

分 类 号：R96[医药卫生—药理学]