半夏泻心汤及其拆方对胃电节律失常大鼠胃电慢波频率变异系数的影响  

Effect of Banxia Xiexin Decoction and Its Components on Coefficient of Variability of Slow Wave Electrogastric Rhythm in Rats with Electrogastric Dysrhythmia

作　　者：李宇航[1] 王庆国[1] 陈萌[1] 李丽娜[1] 王丹[1] 张冬梅[1] 钟相根[1] 王培利[1] 

机构地区：[1]北京中医药大学基础医学院,北京100029

出　　处：《中国中西医结合杂志》2006年第S1期53-55,共3页Chinese Journal of Integrated Traditional and Western Medicine

基　　金：国家自然科学基金项目(No.30271575);教育部优秀青年教师资助计划项目(No.200240)

摘　　要：目的观察半夏泻心汤拆方对胃电节律失常大鼠的影响,探讨该方“消痞散结”的作用机制及其组方配伍规律。方法制备胃电节律失常大鼠模型,检测半夏泻心汤及其拆方对胃电慢波频率变异系数等指标的影响。结果半夏泻心汤及其拆方各组所测胃电慢波频率变异系数减少,与模型组比较,均存在显著差异(P＜0．05)。其中以辛苦组(半夏、干姜、黄芩、黄连)的效果最为显著。结论半夏泻心汤及其拆方各组药物均具有不同程度的纠正胃电节律失常作用,其中辛苦组的作用最强,为进一步认识本方苦降辛开,调畅气机的作用机制,提供了实验依据。Objective To observe the effect of Banxia Xiexin Decoction(BD)and its components in the rats with electrogastric dysrhythmia,explore the mechanism of BD s“relieving distension and fullness,and dissolving lumps”and study BD s compatibility regularity.Methods Rat model of electrogastric dysrhythmia was estab- lished,the effects of BD and its components on the coefficient of variability of the model s slow wave electrogastric rhythm were determined.Results Compared with the model group,BD and all the component...

关 键 词：半夏泻心汤 胃电慢波频率变异系数 拆方研究 

分 类 号：R285[医药卫生—中药学]