颈动脉内中膜厚度和血流剪切力的相关性研究  

Correlative study of intima-media thickness and wall shear stress in common carotid artery

作　　者：庄磊[1] 王伟娟[1] 段云友[2] 阮骊韬[2] 

机构地区：[1]新疆军区总医院医学影像科,新疆乌鲁木齐830000 [2]第四军医大学唐都医院超声科,陕西西安710038

出　　处：《中国临床医学影像杂志》2006年第S1期8-9,共2页Journal of China Clinic Medical Imaging

摘　　要：目的:探讨颈动脉内中膜厚度(IMT)和血流剪切力的关系。资料和方法:采用高分辨力声像仪测量20例健康人颈动脉内中膜厚度,其中男10例,女10例,平均年龄(34.3±10.6)岁。同时测量该处血管的血流剪切力(τm),具体计算公式:τm=η×4×VmFD。通过直线相关分析判定内中膜厚度和血流剪切力的关系。结果:20例健康人平均内中膜厚度为(0.68±0.06)mm,相应的平均血流剪切力为(12.2±3.4)dynesFcm2,二者呈明显负相关(y=0.8174-0.0117xr,=-0.67)。结论:本研究表明颈动脉内中膜厚度和血流剪切力呈负相关,证实血流剪切力可影响颈动脉内中膜厚度的变化,对预测早期动脉粥样硬化有一定意义。Objective: To explore the relationship between intima-media thickness(IMT) and wall shear stress in common carotid artery.Materials and Methods: Intima-media thickness was measured by high resolution ultrasound in common carotid artery of 20 healthy volunteers,10 males,10 females,average age(34.3±10.6)y.Wall shear stress was calculated as the following equation: τm=η×4×Vm/D.Results: The mean IMT of common carotid artery was(0.68±0.06)mm,the mean τm was(12.2±3.4)dynes/cm2.The mean shear stress was inversely ...

关 键 词：颈动脉 超声检查 

分 类 号：R445.1[医药卫生—影像医学与核医学]