基于红外光谱傅里叶变换的SPR分析技术  

New SPR detection technology based on Fourier-transform-infrared

作　　者：彭承琳[1] 杨景涛[1] 顾大勇[1] 史长宁[2] 

机构地区：[1]重庆大学生物工程学院,重庆400044 [2]第三军医大学新桥医院设备科,重庆400037

出　　处：《仪器仪表学报》2006年第z2期1039-1041,共3页Chinese Journal of Scientific Instrument

基　　金：国家自然科学基金(30300326)资助项目

摘　　要：本文介绍了一种新的表面等离子共振(SPR)检测方法,该方法基于红外光谱傅里叶变换技术(FTIR),不同于常规的SPR检测方式,其工作于较宽的红外光谱带上。本文给出了FTIR-SPR的仪器结构图,并详细叙述了FTIR最主要的部分即迈克耳逊干涉仪的工作原理。本文还给出了光学傅里叶变换的数学公式以及物理学解释。在此波段上的SPR具有一些新特性,例如SPR信号很窄,从而角度分辨率很高,以及更深的消逝波探针深度。这将有助于细胞生理、膜生长等相关的生物工程学、生物物理学研究,并且硅在该范围内具有可穿透性,因此有可能实现SPR传感器的微型化。The paper introduces a novel surface plasmon resonance (SPR) detection methods based on Fourier-Transform-Infrared(FTIR-SPR). Differ with the conventional SPR detection, this method works on a broadband wavelength, which is the infrared spectrum. The set-up of FTIR-SPR experimental is also depicted here. Most important part of FTIR is Michelson interferometer, which is explained in detail about its principle. The theory of optic Fourier transform is described by mathematics equations and physics interpretation. Some interesting characteristics of SPR in this band,such as very high angular resolution and deep evanescent wave probe,may help cell, membrane and related research on Bioengineering and Biophysics. We show that silicon is transparent in this range, which is very useful with respect to SPR sensor miniaturization and integration.

关 键 词：表面等离子共振 红外光谱 傅里叶变换 干涉 

分 类 号：TH7-55[机械工程—仪器科学与技术]