甲状腺机能亢进性肌病的诊断与治疗  

Diagnosis and treatment of thyrotoxicmyopathy

作　　者：马德奎[1] 冯平[1] 黄擎雄[1] 吴志扬[1] 曾海锋[1] 任朝林[2] 陈伯棠[1] 李风云[1] 张美华[2] 

机构地区：[1]广东省肇庆市第一人民医院普通外科,广东肇庆526020 [2]肇庆医学高等专科学校附院外科,广东肇庆526021

出　　处：《中国现代医学杂志》2006年第24期3771-3773,3776,共4页China Journal of Modern Medicine

摘　　要：目的探讨甲状腺机能亢进性肌病(甲亢性肌病)的诊断与治疗,减少临床误诊误治。方法回顾性分析1994年1月￣2004年1月收治76例甲亢性肌病的临床资料。结果76例中有48例确诊前被误诊为其他疾病,误诊率高达63.16%;慢性甲亢性肌病、周期性麻痹及重症肌无力是主要的临床类型;40例双侧甲状腺全切除术,36例采用药物治疗。随访2年,手术治疗组甲亢复发2例,其中伴肌病复发1例;药物治疗组甲亢复发21例,其中伴肌病复发15例。两组间对比差异有显著性(P<0.005)。结论甲亢性肌病临床表现复杂多样,具有个体化的特点,误诊率高;加强对该病的认识和完善的实验室检查,可有效减少误诊机会;手术治疗是治愈甲亢性肌病的首选方法。[Objective] To explore the diagnosis and treatment of thyrotoxicmyopathy. So as to reduce chance of diagnosis and therapy wrongly. [Methods] The clinical data of 76 cases with thyrotoxicmyopathy were reviewed and analyzed retrospectively. [Results] In 76 patients with thyrotoxicmyopathy, 48 cases were misdiagnosed. The main clinical types included chronic thyrotoxicmyopathy and periodical paralysis and serious myasthenia. 40 cases were performed subtotal thyroidectomy and 36 cases were treated with anti-thyroid drugs. All cases were followed up two years respectively. The results showed 2 cases were recurrence hyperthyroidism in operations group and 21 cases in drugs group combined myopathy. The therapeutic effects were significant differences between operation group and drug-therapy group. [Conclusions] Patients with thyrotoxicmyopathy have kinds of clinical symptoms and individual characteristic. The error diagnosis rate of this diseases was high. Understanding well this disease and total experimental examination could reduce the rate of error diagnosis effectively. Surgical treatment should be the first selection to treat thyrotoxicmyopathy.

关 键 词：甲亢性肌病 诊断 治疗 

分 类 号：R581.1[医药卫生—内分泌]