HPLC测定木香顺气丸中的4种有效成分  

Determination of four effective components in Muxiang Shunqi pills by HPLC

作　　者：孙全明[1] 朱朝德[1] 李春雨[1] 

机构地区：[1]安康市药品检验所,陕西安康725000

出　　处：《华西药学杂志》2008年第2期215-216,共2页West China Journal of Pharmaceutical Sciences

摘　　要：目的采用HPLC法同时测定木香顺气丸中木香烃内酯、去氢木香烃内酯、厚朴酚和厚朴酚的含量。方法采用Kro-masil C18色谱柱(250 mm×4.6 mm,5.0μm),流动相为乙腈-甲醇-水(50:8:42);检测波长210 nm;流速1.0 m.lmin-1。结果木香顺气丸中4种指标成分的线性关系良好,r为0.9996~0.9999;回收率为97.49%~100.80%,RSD为0.88%~1.77%。结论所建方法专属性强、重复性好,可用于木香顺气丸的质量控制。OBJECTIVE To establish a method for determination of costunolide,dehydrocostuslactone,magnolol and honokiol in Muxiang Shunqi pills by HPLC.METHODSKromasil C18(250 mm×4.6 mm,5.0 μm)was used with the mobile phase consisted of acetonitrile-menthanol-water(50:8:42).The flow rate was 1.0 ml·min-1 with the detection wavelength at 210 nm.RESULTSThe linear range of the method was 0.9996 to 0.9999.The average recovery was 97.5%-100.8% with corresponding RSD of 0.88%-1.77%.CONCLUSIONThe method is specific and repeat...

关 键 词：高效液相色谱法 木香顺气丸 木香烃内酯 去氢木香烃内酯 厚朴酚 和厚朴酚 

分 类 号：R286[医药卫生—中药学]