菌体抗原“缺失”的宋内氏志贺菌研究  

Study on Shigella sonnei with"no"O antigen

作　　者：何啸[1] 陈宗宁[1] 邵荣标[2] 王海燕[2] 王荣堂[3] 

机构地区：[1]南通大学第四附属医院,盐城224006 [2]江苏省盐城市疾病预防控制中心 [3]盐都区疾病预防控制中心

出　　处：《南通大学学报（医学版）》2008年第4期274-275,共2页Journal of Nantong University(Medical sciences)

摘　　要：目的:研究O抗原"缺失"的宋内氏志贺菌其它生物学性状的变化情况。方法:检测试验菌株的生化特性和对抗生素的敏感性,以及用多种批号的诊断血清进行凝集试验。结果:具有典型的宋内氏志贺菌的生化特性;与对照菌相比,有较高抗生素耐药性,对复方新诺明等多种抗生素耐药。与效期内的多批宋内氏志贺菌诊断血清不能产生凝集反应,而对照菌凝集良好。结论:该株宋内氏志贺菌的O抗原表达减弱,同时药敏谱也产生明显的改变。Objective:To study the other properties of Shigella sonnei with"no"O antigen.Methods:The biochemistry properties and the sensitivity to antibiotics of studied bacillus were tested,and the O antigen of studied bacillus was tested with slider agglutination test.Results:The strain of studied Shigella sonnei had the representative biochemical properties of Shigella sonnei.Contrasting with the control strain of Shigella sonnei,the test strain could be higher antibiotics rate,and it could not be agglutinated by s...

关 键 词：宋内氏志贺菌 O抗原 变异 

分 类 号：R446.5[医药卫生—诊断学]