乳癖康合剂治疗乳腺增生病的临床研究  

Clinical Study on Treatment of Cyclomastopathy with Rupikang Mixture

作　　者：李湘奇[1] 孙国权[2] 

机构地区：[1]山东中医药大学,山东250014 [2]山东省滕州市中医医院,山东277500

出　　处：《北京中医药大学学报（中医临床版）》2005年第6期1-4,共4页Journal of Beijing University of Traditional Chinese Medicine

基　　金：山东省枣庄市科技局基金项目(No.ZK2003046)

摘　　要：目的探讨乳癖康合剂治疗乳腺增生病的临床疗效。方法将215例乳腺增生病患者随机分为治疗组(165例,口服乳癖康合剂)和对照组(50例,口服乳安片),分别观察2组临床疗效、止痛效果、肿块缓解情况及治疗前后乳腺血流动力学和性激素水平的变化。结果治疗组总有效率为92.73%,与对照组比较有显著性差异(P<0.01)。治疗组止痛及肿块缓解效果优于对照组(P<0.01)。治疗组治疗后雌二醇和垂体促乳素显著降低(均P<0.05),而孕激素和雄激素则有回升(均P<0.05),并能减少病变区的血流信号和阻力指数(均P<0.05)。结论乳癖康合剂治疗乳腺增生病具有显著的临床疗效。Objective To discuss the curative effect of Rupikang Mixture on cyclomastopathy. Method To divide randomly 215 cases of cyclomastopathy into the treatment group (n=165) and the control group (n=50), and then treat them orally with Rupikang Mixture and Ru`an Tablets respectively. The curative and analgesic effects, relief of swelling and hemodynamics, the changes of sex hormones levels before and after the treatment in two groups were observed. Result The total effective rate of the treatment group was 92.73 % and had a significant difference compared with that of the control group (P<0.01), The analgesic effect and relief of swelling in the treatment group was better than that of the control group (P<0.01). In the treatment group the levels of estradiol (E2) and prolactin (PRL) decreased obviously after the treatment (P<0.05). The levels of progestagen (P) and androgen increased (P<0.05), and the blood signal and impedance index decreased in pathological area (P<0.05). Conclusion Rupikang Mixture has a reliable curative effect on cyclomastopathy.

关 键 词：乳癖康合剂 乳腺增生病 性激素 血流动力学 

分 类 号：R271.44[医药卫生—中医妇科学]