自然对流型PCR芯片的热分析与设计  

THERMAL ANALYSIS AND DESIGN OF NATURAL CONVECTION PCR CHIP

作　　者：薛辉[1] 王玮[1] 李志信[1] 过增元[1] 

机构地区：[1]清华大学航天航空学院,北京100084

出　　处：《工程热物理学报》2005年第z1期140-142,共3页Journal of Engineering Thermophysics

基　　金：国家自然科学基金重大资助项目(No.59995550-2)

摘　　要：在分析了现有自然对流型PCR芯片的热性能的基础上,提出了采用薄圆盘腔体内Rayleigh-Benard对流实现PCR过程,并通过数值模拟研究了几何尺寸对自然对流稳定性的影响以及腔体内不同位置处流体温度随时间的变化。模拟结果表明通过几何尺寸的优化能够实现稳定的Rayleigh-Benard对流和PCR过程。Based on the analysis of the thermal performance of the existing natural convection poly-merase chain reaction (PCR), a Rayleigh-Benard convection in a flat cylinder chamber was proposed to realize two-temperature PCR. The effect of the chamber dimensions was numerically studied. Natural convention was proposed to realize polymerase chain reaction. The results indicated that in the optimized flat cylinder chamber, a steady Rayleigh-Bfnard convection can be formed, thereby a robust two-temperature polymerase chain reaction can be achieved.

关 键 词：微PCR芯片 自然对流 瑞利数 

分 类 号：TK124[动力工程及工程热物理—工程热物理]