一种基于磁声电相互耦合的神经电流检测方法  

A Method of Coupling of Magnetics, Acoustics and Electrics for the Measurement of Neural Currents

作　　者：杨少华[1] 刘军[1] 张虹淼[1] 楼正国[1] 李光[1] 

机构地区：[1]生物医学工程教育部重点实验室浙江大学生物医学工程系,杭州310027

出　　处：《仪器仪表学报》2005年第z1期31-32,42,共3页Chinese Journal of Scientific Instrument

基　　金：国家自然科学基金(30470470)资助项目

摘　　要：提出了一种基于磁声电相互耦合的神经电流检测方法。对溶液、凝胶和生物组织外加一个恒稳磁场和一个交变电场,两者耦合产生洛仑兹力。变化的洛仑兹力使媒质中的离子发生振动,这个振动可由外部的声传感器灵敏而无创地检测到。对模拟的神经进行检测,实验结果显示本方案取得很好的效果,在此基础上可以进一步以磁声电耦合方式实现生物组织电阻抗特性或神经电传导能力的评估。A novel method of coupling magnetics, acoustics and electrics is presented to measure neural currents. When oscillating electricity applied on a nerve model, which consists of saline, gel and tissue, in a steady magnetic field, the coupling of the oscillating electric and steady magnetic fields generates a Lorentz force. The time-varying Lorentz force causes ions vibrate in the medium, which can be detected by a sensitive acoustic sensor non-invasively. An experimental setup is designed to detect current through the nerve model and the minimal detectable current is 1μA. This approach has potential to evaluate other characteristics of tissue resistance and nerve conduction as well as neural currents.

关 键 词：神经电流检测 磁声电耦合 洛仑兹力 纳维-斯托克斯方程 

分 类 号：TH7-55[机械工程—仪器科学与技术]