复方异丙嗪滴鼻液中异丙嗪和麻黄碱含量测定  

Determination of promethazine hydrochloride and ephedrine hydrochloride in compound nasal drops

作　　者：李炜清[1] 黄心一[1] 赖林[1] 

机构地区：[1]成都市第三人民医院药剂科,四川成都610031

出　　处：《中国现代应用药学》2005年第z1期632-633,共2页Chinese Journal of Modern Applied Pharmacy

摘　　要：目的建立不经分离测定复方滴鼻液中盐酸异丙嗪和盐酸麻黄碱的含量。方法差示分光光度法、旋光度法。结果盐酸异丙嗪和盐酸麻黄碱的平均回收率分别是99.63%(RSD:0.52%,r=0.9999,n=7)和99.84%(RSD:0.37%,r=0.9998,n=7)。结论方法简便、快速、准确。OBJECTIVE To establish a method for determination of promethazine hydrochloride and ephedrine hydrochloride in compound nasal drops without need of separation.METHODS Differential spectrophotometry and polarimetry.RESILTS The average recvery rates of promethazine and ephedrine were 99.63%(RSD:0.52%,r = 0.9999,n =1) and 99.84%(RSD:0.37%,r=0.9998,n = 7).CONCLUSION This method is simple,rapid,accurate.

关 键 词：盐酸麻黄碱 盐酸异丙嗪 差示分光光度法 旋光度法 

分 类 号：R917.7.2[医药卫生—药物分析学]