感愈灵泡腾片的制备及其质量控制  

Prepareation and quality of Ganyuling effervescent tablet

作　　者：袁伟清 谢瑛[2] 

机构地区：[1]深圳市横岗人民医院,广东深圳518115 [2]深圳市蛇口人民医院,广东深圳518067

出　　处：《中国现代应用药学》2005年第z2期776-777,共2页Chinese Journal of Modern Applied Pharmacy

摘　　要：目的制备感愈灵泡腾片并对其进行质量控制。方法采用薄层色谱法鉴别盐酸麻黄碱;建立HPLC控制葛根素的含量,采用Hypersil—C_(18)((?)4.6mm×200mm,5μm)色谱柱,流动相为甲醇—重蒸水(25:75),检测波长250nm。结果该含量测定方法的线性范围为0.1224~0.6120μg(r=0.9997,n=5),平均加样回收率为99.5%,RSD=1.48%(n=5)。结论感愈灵泡腾片制备工艺简便可行,含量测定快速准确,可用于该制剂的质量控制。OBJECTIVE To prepare the Ganyuling effervescent tablet and establish the standard of quality control.METHOD Efedria hydrochloric was identified by TLC.Content of kakonein was controled by HPLC.HPLC was performed on Hypersil-C18 column with methanol-water(25:75) as the mobile phase and detection at 250 nm.RESULTS The calibration curve of the method was linear within the range of 0.1224μg^0.6120μg(r=0.997,n=5).The average recovery rate was 99.5%.RSD = 1.48%(n =5).CONCLUSION The Canyuling effervescent tablet was feasible in technological process.The method of content determination is simple and accurate.

关 键 词：感愈灵 泡腾片 质量控制 

分 类 号：R283.6[医药卫生—中药学]