升阳益胃汤抗疲劳的实验研究  

The Anti-Fatigue Study of the Decoction of Shengyang Yiqi

作　　者：冯玉华[1] 阎润红[1] 段剑飞[2] 

机构地区：[1]山西中医学院方剂教研室,山西太原030024 [2]山东万杰医学高等专科学校中医教研室,山东淄博255213

出　　处：《中国实验方剂学杂志》2008年第8期60-62,共3页Chinese Journal of Experimental Traditional Medical Formulae

摘　　要：目的:通过对升阳益胃汤抗疲劳的实验研究,来评价"消补兼施"法在抗疲劳中的作用,为抗疲劳提供新的研究思路。方法:昆明种雄性小鼠90只(经游泳能力初筛),随机分为三组,分别为空白对照组,升阳益胃汤组及阳性对照组(螺旋藻)。采用小鼠游泳制备疲劳模型的方法,连续灌胃给药15d,20g小鼠灌胃量0.4mL。分别观察各组对小鼠负重游泳运动时间、小鼠游泳运动10min后和游泳运动后休息15min血乳酸变化值、血清尿素氮、肝糖原和肌糖原的影响。结果:升阳益胃汤能显著提高小鼠的运动耐力,延长小鼠的游泳运动时间;能显著降低小鼠游泳运动10min后血乳酸升高值,减少血清尿素氮的产生,但对肝糖原和肌糖原含量无影响。结论:升阳益胃汤具有抗疲劳功效,且在应用15d时能对小鼠发挥其抗疲劳作用。Objective:Through the anti-fatigue study of the decoction of Shengyang Yiqi to evaluate the therapeutic principle of removing and reinforcing on the anti-fatigue and to offer a new idea for anti-fatigue.Method:Ninety selected male mice(through swimming ability as preliminary screening) were divided randomly into 3 groups.They were blank control group,decotion of raising splen-yang to tonify stomach group,positive control group(spirulina).The time of burden swimming,the increase of LA after 10 min swimming,t...

关 键 词：升阳益胃汤 中药复方 抗疲劳 

分 类 号：R285.5[医药卫生—中药学]