急性心肌梗死严重程度与体内胰岛素抵抗水平的相关性  

The relationship between insulin resistance and the severity extent of acute myocardial infarction

作　　者：张莉[1] 杨永滨[2] 任金金[2] 商琰红[2] 袁芳[3] 

机构地区：[1]河北省老年病医院,石家庄050011 [2]河北大学医学部,071000 [3]保定市第一医院

出　　处：《疑难病杂志》2008年第7期388-389,共2页Chinese Journal of Difficult and Complicated Cases

摘　　要：目的探讨胰岛素抵抗水平与急性心肌梗死(AMI)患者病情严重程度相关性及其临床意义。方法分别检测122例AMI患者观察组和50例健康对照组(A组)入院第1天的空腹血糖及胰岛素,并计算其胰岛素抵抗指数(IR)。观察组根据AMI患者入院病情和Killip分级标准将其进行分组,其中I级和II级(B组)99例,III级和IV级(C组)23例。观察AMI严重程度与空腹血糖、空腹胰岛素以及IR的相关性。结果B组和C组空腹胰岛素[(9.7±3.6)mU/L和(11.8±3.8)mU/L]均明显高于A组(7.6±2.3)mU/L(P<0.05),IR值(2.53±0.09和3.34±0.42)也明显高于A组(2.07±0.10)(P<0.05);C组空腹血糖、空腹胰岛素、IR与B组相比差异有统计学意义(P<0.05)。各组病变程度分级指数与IR之间呈正相关(r2=0.913,P<0.01)。结论AMI患者早期IR水平可以反映病情的严重程度。Objective To explore the relationship and clinical significance between insulin resistance(IR)and the severity extent of acute myocardial infarction(AMI).Methods The fasting blood glucose was measured overnight in 122 patients(observation group)with AMI and 50 healthy persons(control group,group A),and the insulin resistance(IR)was calculated according to the formula of HOMA-IR.The patients in the observation group were divided into group B(Killip class I and II,99 cases)and group C(Killip class III and IV,...

关 键 词：心肌梗死 急性 胰岛素抵抗 KILLIP分级 

分 类 号：R542.22[医药卫生—心血管疾病]