巴戟天醇提物与水提物对D-半乳糖所致衰老小鼠血细胞的影响  

Morinda officinalis alcohol mentions a thing and aqueous extract is caused by galactose to D-growing old small rat blood cell effect

作　　者：王红丽 李东东 甄锦芳 林悦燕 张翠玲 卢小凤 林丹丹 Wang Hongli Li Dongdong Zhen Jinfang Lin Yueyan Zhang Cuiling Lu Xiaofeng Lin Dandan;

机构地区：广东药学院临床医学院,510305

出　　处：《中外健康文摘：临床医师》2008年第6期34-35,共2页

基　　金：2006年广东省中医药局课题[NO.2060043]

摘　　要：目的:比较巴戟天醇提物与水提物对衰老小鼠外周血细胞的影响,从而探讨巴天戟天抗衰老作用机制。方法:采用颈背部皮下注射D-半乳糖制造小鼠衰老模型,分别灌服各剂量的巴戟天醇提物和水提物,42d后,断尾取血检测外周血常规值。结果:与模型组比较,随着巴戟天水提物含量的升高,红细胞、血小板、血红蛋白含量逐渐增高,差异有统计学意义;巴戟天醇提物除高剂量组血小板数量与模型组比较差异有显著性差异外,其他指标改变不明显。结论:巴戟天水提物有明显提升衰老小鼠红细胞和血小板数量的作用,高剂量提升效果更显著;而巴戟天醇提物对衰老小鼠升血细胞作用不明显。表明巴戟天提升血细胞的成分主要存在于水提物中,支持了临床上巴戟天补肾阳、强筋骨功效的理论,并宜水煎剂服用的传统用法。Purpose:Morinda officinalis alcohol carries an impact of thing and aqueous extract over small rat outside cycle old and feeble blood cell comparatively,discuss bar of day halberd sky thereby resisting the effect old and feeble mechanism.Method:Adopt the scruff part hypo D-galactose to make the model of small rat old and feeble,the Morinda officinalis alcohol drinking wine respectively being accustomed to every dosages mentions after the thing and water mention things,42 ds,cut off a tail taking blood detect...

关 键 词：巴戟天 乙醇提取物 D-半乳糖 血细胞 

分 类 号：R285.5[医药卫生—中药学;医药卫生—中医学]