Calix[4]arene-Based New Neutral Sensors for Fluoride  

作　　者：LIU,Shun-Ying MENG,Ling-Zhi LIU,Xin HE,Yong-Bing 

机构地区：[1]Department of Chemistry, Wuhan University, Wuhan 430072 Department of Chemistry, Wuhan University, Wuhan 430072 Department of Chemistry, Wuhan University, Wuhan 430072 Department of Chemistry, Wuhan University, Wuhan 430072

出　　处：《有机化学》2004年第z1期276-,共1页Chinese Journal of Organic Chemistry

基　　金：Project supported by the National Natural Science Foundation of China (No. 20372054).

摘　　要：　　The development of new receptors which can recognize neutral and charged species has attracted considerable interest in the recent past.[1] Anions such as fluoride, chloride, phosphate and carboxylate play crucial roles in a range of biological phenomena and are implicated in many disease states.[2] Investigations on molecular and/or ionic recognition by calixarenes and their derivatives as synthetic receptors have attracted increasing attention in supramolecular chemistry because of their modifiable structure.[3] However, calix[4]arenes-based neutral receptors containing thiourea and amide groups are still rare. In this paper, we report fluoride selective optical chemosensors 4 and 5, based on calix[4]arene thiourea and amide derivatives, which only show a remarkable absorption change in the presence of fluoride ions, while have no any change upon addition of other anions (Cl- Br-, I-, AcO- and H2PO4-). The association constants are 947 and 2883 mol·L-1, respectively. The synthesis of calix[4]arene derivatives 4 and 5 is outlined in the following Scheme 1.……

分 类 号：O62[理学—有机化学]