中毒患者血清和尿液中毒鼠强残留物的GC-MS分析方法  

A Method for Rapid Determination of Tetramine Residues in Serum and Urine of Patient by GC - MS

作　　者：苏小川[1] 覃志英[1] 冯向阳[1] 

机构地区：[1]广西壮族自治区疾病预防控制中心,广西南宁530021

出　　处：《分析测试学报》2004年第z1期58-61,共4页Journal of Instrumental Analysis

摘　　要：　　有关资料表明[1],人和动物口服毒鼠强后,其血液、尿液和各脏器中均有毒鼠强残留物出现,残留时间从药后数小时至几天乃至十几天之内不等.可见血液和尿液作为可印证中毒病人中毒原因的直接样品更值得我们去关注,与呕吐物、可疑食物等检品相比[2,3],它具有提取相对简单,干扰成分少,残留时间长以及可反复采集等许多优点.……This paper describes a method for rapid determination of tetramine residues in serum and urime by high performance untrasonic extraction with GC - MS. The result showed that the recovery rate of tetramine in blood serum were 90.8% to 99.5% , RSD was 3.82%. The recovery rate of tetramine in urine were 91.2% to 102.8% , RSD was 4.91% . The limit of detection(LOD) was 0.001 mg/L. The proposed mothod has been applied to the daily analyzing tetramine residues in serum and urine of patient and that with satisfactory results.

关 键 词：SERUM URINE TETRAMINE GC-MS 

分 类 号：O657-55[理学—分析化学]