金叶败毒方之免煎颗粒与传统饮片对小鼠抗炎及免疫功能影响的比较研究  

Comparative Study on Anti-inflammation and Immune Function of Mice between Extracted Granule Preparation and Traditional Herbal Decoction of Jinye Baidu Recipe

作　　者：陆付耳[1] 邹欣[1] 徐丽君[1] 王开富[1] 叶望云[1] 

机构地区：[1]华中科技大学同济医学院附属同济医院中西医结合研究所,武汉430030

出　　处：《中国中西医结合杂志》2004年第S1期157-160,共4页Chinese Journal of Integrated Traditional and Western Medicine

摘　　要：目的探讨金叶败毒方之免煎颗粒与传统饮片在抗炎及增强免疫功能等药效方面的差别。方法分别以昆明种小鼠建立炎症和免疫功能低下动物模型,分别对金叶败毒方之免煎颗粒与传统饮片设立大、小剂量组;采用经典的小鼠耳肿实验和血管通透性实验验证金叶败毒方的抗炎功效,而以小鼠腹腔巨噬细胞吞噬实验和溶血素测定实验为反映免疫功能的指标。结果金叶败毒方之免煎颗粒与传统饮片均有抗炎和增强免疫功能的作用,且两种制剂之大剂量组疗效均优于小剂量组;免煎颗粒大剂量组的抗炎功效与传统饮片小剂量组相当。结论金叶败毒方之免煎颗粒具有与传统饮片相同的抗炎与增强免疫功能的功效,适当增加其剂量可望达到与传统饮片同等强度的治疗效应。Objective To explore the difference in anti-inflammation and enhancing immune function between Extracted Gran- ule Preparation(EGP)and Traditional Herbal Decoction(THD)of Jinye Baidu Recipe(JBR).Methods Animal model of inflammation and cyelophosphamide-induced immune dysfunction in Kuming mice was founded.Large and small dosage groups of EGP and THD were set up.Classic experiments of mice ear swelling and vascular permeability were adopted to verify the effect of JBR,while the immune function was reflected ...

关 键 词：金叶败毒方 免煎颗粒 传统饮片 抗炎 免疫 

分 类 号：R285.5[医药卫生—中药学]