Amino Acids Catalyzed Direct Aldol Reactions in Aqueous Micelles  

作　　者：PENG Yi-Yuan WANG Qi DING Qiu-Ping HE Jia-Qi CHENG Jin-Pei 

机构地区：[1]Department of Chemistry, Nankai University, Tianjin 300071 [2]Department of Chemistry, Jiangxi Normal University, Nanchang 330027 Department of Chemistry, Nankai University, Tianjin 300071 Department of Chemistry, Jiangxi Normal University, Nanchang 330027 Department of Chemistry, Nankai University, Tianjin 300071 Department of Chemistry, Nankai University, Tianjin 300071

出　　处：《有机化学》2003年第z1期178-179,共2页Chinese Journal of Organic Chemistry

基　　金：Project supported by the National Natural Science Foundation of China (No. 29928004) and the Natural Science Foundation of Jiangxi Province (No. 9920002).

摘　　要：　　Since the discovery of its roles as a good small-organic-molecule catalyst in intramolecular aldol reactions, pro line has drawn considerable attention in synthetic chemistry due to its similarity to the type-Ⅰ aldolases. Recently,List and others have reported some new direct asymmetric intermolecular reactions catalyzed by proline, including aldol, Mannich, Michael, and other analogous reactions. Except for two recent examples, [1,2] proline catalyzed aldol reactions in aqueous micelles have not been reported, nor have other amino acids as organocatalysts in directly catalyzing aldol reaction been reported. Herein we wish to present our recent results regarding environmentally be nign direct aldol reactions catalyzed by amino acids including proline, histidine and arginine in aqueous media.……

分 类 号：O62[理学—有机化学]