Synthesis and Chiral Recognition of Novel Chiral Macrocyclic Dioxopolyamines Derived from L-Proline  

作　　者：YANG Xue-Mei LIU Ling-Yan LI Bao-Hua XUE Peng FU En-Qin 

机构地区：[1]Department of Chemistry, Wuhan University, Wuhan 430072 Department of Chemistry, Wuhan University, Wuhan 430072 Department of Chemistry, Wuhan University, Wuhan 430072 Department of Chemistry, Wuhan University, Wuhan 430072 Department of Chemistry, Wuhan University, Wuhan 430072

出　　处：《有机化学》2003年第z1期251-251,共1页Chinese Journal of Organic Chemistry

基　　金：Project supported by the National Natural Science Foundation of China (No. 20272045).

摘　　要：　　Recently, much concentration has been focused on chiral macrocyclic amides that bear the dual features of macrocyclic polyamines and oligopeptides, which can act as both hydrogen bond acceptors and donors and can form complexes with cation, anion or neutral molecules, so as to have potential applications for enantiomeric recognition and enantiomeric separation. In light that the more rigid the macrocyclic molecule, the better the enantiomeric recognition, and macrocyclic receptors possessing C2 symmetry usually show higher enantioselectivity than those of C1 symmetry, we chose L-proline, which possesses a unique and rigid pyrrolidinyl group, as starting material to synthesize a new class of novel chiral macrocyclic dioxopolyamines of C2 symmetry. ……

分 类 号：O62[理学—有机化学]