Synthesis of Gibbilimbols A ～ D and Their ( Z )-Isomers  

作　　者：ZHOU Ling YANG Yong-Gang CAO Xiao-Ping 

机构地区：[1]National Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000 National Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000 National Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000

出　　处：《有机化学》2003年第z1期439-439,共1页Chinese Journal of Organic Chemistry

基　　金：Project supported by the National Natural Science Foundation of China (QT program No. 20021001 ).

摘　　要：　　Gibbilimbols (1) were isolated from the leaves of Piper gibbilimbum in Papua New Guinea, which showed cyto toxicity toward KB nasopharyngal cancer cells (EDs0 2～ 8 μg/mL) and antibacterial activity against Staphylococcus epidermidis and Bacillus cereus (MIC 2 ～4 μg/mL). [1] Only two methods were reported for the synthesis of them,one is a coupling of phenolic part with alkyne, followed by reduction of triple bond by Mori. [2]……

分 类 号：O62[理学—有机化学]