An Efficient Protocol for the Reduction of Azidonucleosides Catalyzed by Raney Nickel  

An Efficient Protocol for the Reduction of Azidonucleosides Catalyzed by Raney Nickel

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作  者:QU Gui-Rong LIU Qi-Bin 

机构地区:[1]Key Laboratory of Environmental Science and Technology of High Education of Henan Province, College of Chemical and Environmental Science, Henan Normal University, Xinxiang 453002 Key Laboratory of Environmental Science and Technology of High Education of Henan Province, College of Chemical and Environmental Science, Henan Normal University, Xinxiang 453002

出  处:《有机化学》2003年第z1期104-105,共2页Chinese Journal of Organic Chemistry

基  金:Project supported by the National Natural Science Foundation of China (No. 29972010).

摘  要:  Aminonucleosides are very important intermediates in the synthesis of anti-sense and anti-gene drugs, nucleic acid analogues, diagnostic and analytical agents, antitumor and antiviral compounds. In the presence of Raney nickel, the reduction of various azidonucleosides to the corresponding aminonucleosides is in good yields (Table 1,Scheme 1).……

分 类 号:O62[理学—有机化学]

 

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