补肾复方冲剂对慢性再生障碍性贫血患者红细胞免疫黏附功能和膜分子CD35、CD58表达的影响  

Influence of Bu-Shen-Compound on adhesive function and the expression of erythrocyte molecule- CD35 and CD58 of erythrocytes in patients with chronic aplastic anemia

作　　者：代喜平[1] 王运律[2] 朱宇清[2] 应平平[2] 胡琦[2] 吴正翔[2] 

机构地区：[1]广东省中医院二沙岛分院内7科,广东广州510120 [2]上海市中医院,上海200051

出　　处：《免疫学杂志》2003年第S1期43-44,47,共3页Immunological Journal

基　　金：上海市教委发展基金(99C104)

摘　　要：目的 探讨补肾复方冲剂对慢性再生障碍性贫血(以下简称慢性再障,CAA)患者红细胞免疫黏附功能和膜分子CD35、CD58表达的影响。方法 以补肾复方冲剂治疗CAA患者6个月,,检测正常对照组与慢性再障组治疗前后红细胞C_(3b)受体花环率(RBC-C_(3b)RR)、红细胞免疫复合物花环率(RBC-ICR)、红细胞膜CD35、CD58分子定量。结果 慢性再障组治疗前RBC-C_(3b)RR、膜CD58分子定量均明显低于正常对照组(P<0.01),RBC-ICR、膜CD35分子定量与正常对照组相比,差异无显著性(P>0.05);治疗后RBC-C_(3B)RR、膜CD58分子定量明显升高,与治疗前比较有显著性差异(P<0.05或P<0.01)。结论 补肾复方冲剂能提高CAA患者红细胞免疫黏附功能和膜分子CD58表达水平。Objective To investigate the influence of Bu-Shen-Compound on erythrocyte s adhesive function, the expression of erythro-cyte molecule-CD35 and CD58 of erythrocytes in patents with chronic aplastic anemia(CAA) .Methods 30 CAA patients were given Bu-Shen-Compound for 6 months. We observe following items of the CAA group:the C3b, receptor wreath rate(RBC-C3bRR) ,IC wreath rate(RBC-ICR), the expression of erythrocyte molecule-CD35 and CD58 of the erythrocytes before and after the treatment. We also detected t...

关 键 词：贫血 再生障碍性 红细胞免疫 免疫分子 补肾复方冲剂 

分 类 号：R259.5[医药卫生—中西医结合]