保元丹对小鼠免疫功能的实验研究  

Experimental study of Bao Yuan Dan (BYD) on the inununological function in mouse

作　　者：金道山[1] 梅士昌[1] 王锦传[1] 赵美玲[1] 赵冠英[1] 

机构地区：[1]解放军总医院成果转化中心,北京100853

出　　处：《免疫学杂志》2003年第S1期39-40,42,共3页Immunological Journal

摘　　要：目的 了解保元丹对机体免疫功能的影响。方法 采用Balb/c健康雌性小鼠为实验动物模型,检测了保元丹对淋巴细胞转化值,半数溶血值,抗体生成细胞数,迟发性变态反应以及NK细胞活性的影响。结果 与对照组相比,保元丹高剂量组能显著提高小鼠血清溶血素半数溶血值(P<0.05)。中高剂量能显著提高小鼠淋巴细胞转化值和迟发性变态反应(P<0.05)。低中高3个剂量都能显著提高抗体生成细胞数和NK细胞活性(P<0.01)。结论 保元丹既能增强特异性免疫又能增强非特异性免疫,表明保元丹具有提高机体免疫功能的作用。Objective To study the effect of BYD on the immunological function in mice.Methods Balb/c female mice were used as the model of the test animal. The effect of BYD on the change ratio of lymphocyte in mouse spleen, and the half number hemolysis rate in mouse serum, the cell number of antibody produced in mouse spleen, the delayed hypersensitivity in mouse, and the activity of the natural killer (NK) cell in mouse spleen were studied. Results Compared with the blank control group, BYD can significantly raised...

关 键 词：保元丹 免疫功能 实验研究 

分 类 号：R285.5[医药卫生—中药学]