前列地尔治疗慢性肾功能不全临床观察  

Clinical observation of chronic renal failure treated with alprostadil

作　　者：林建昌[1] 宋玉清[1] 邱维强[1] 

机构地区：[1]广东梅州市人民医院,514031

出　　处：《中国基层医药》2003年第11期28-29,共2页Chinese Journal of Primary Medicine and Pharmacy

摘　　要：目的　探讨前列地尔 (PGE1)治疗慢性肾功能不全 (CRF)的临床疗效。方法　治疗组与对照组均采用非透析治疗 ,常规用药相同 ,治疗组加用PGE1静脉滴注 ,每天 1次 ,连续 3周。结果　治疗组治疗后 ,尿量增加占 87 5 % ,血肌酐下降占 92 5 % ,尿素氮下降占 77 5 % ,尿酸下降占 75 0 % ,未经补碱治疗的代谢性酸中毒减轻占 6 7 5 % ,尿蛋白轻微减少占 4 5 0 % ,综合各项疗效情况显示 ,治疗组优于对照组。结论　CRF应用PGE1治疗后 ,病人尿量增加 ,血肌酐、尿素氮和尿酸下降 ,在改善代谢性酸中毒方面优于一般非透析的对照组。Objective To study the clinical effect of lipo-corpuscule coated alprostadil(prostaglandin E 1,PGE 1,qianliedi er zhusheye) on chronic renal failure.Methods The traditional non-dialysis therapy was given to the PGE 1-treated group and the control group simultaneously,but an additional PGE 1 was given to treated group(ivgtt,1/d,3w).Results After treatment,87.5% of patients in PGE 1-terated group had increased urine volume.The decline of CR,BUN,uric acid was found respectively in 92.5%,77.5% and 75% o...

关 键 词：前列地尔 脂微球 慢性肾功能不全 

分 类 号：R692.5[医药卫生—泌尿科学]