艾滋病合并结核病与CD4 T淋巴细胞计数的相关性研究  

Correlation between AIDS with tuberculosis and CD4T lymphocyte count

作　　者：孙燕[1] 赵清霞[1] 何云[1] 刘建民[1] 崔帷 

机构地区：[1]河南省郑州市第六人民医院,郑州450015

出　　处：《中国防痨杂志》2008年第5期427-430,共4页Chinese Journal of Antituberculosis

摘　　要：目的通过对AIDS合并结核病例的回顾性分析,探讨AIDS合并结核病临床特征与CD4 T淋巴细胞计数的相关性。方法对95例AIDS并发结核感染的病例CD4 T淋巴细胞计数进行检测,同时选择30例近期入院的HIV阴性肺结核病人CD4 T淋巴细胞计数的检测,AIDS合并结核病与HIV阴性肺结核病CD4 T淋巴细胞水平对比分析;AIDS合并结核中PPD、结明试验、结核分型与CD4 T不同水平进行相关性分析。结果AIDS合并结核病与HIV阴性结核病CD4 T淋巴细胞水平相比,二者有显著性差异;CD4 T淋巴细胞计数与艾滋病合并结核病的影象学表现;PPD、结明试验、痰涂片抗酸染色阳性率、结核病分型有相关性,CD4<100/mm3与CD4>100/mm3相比,影象学中斑片实变影、多发空洞、多发结节、纵隔和(或)腋下淋巴结肿大有显著性差异;单发空洞,胸腔积液的机率,无显著性差异。CD4<100/mm3与CD4>100/mm3相比,PPD、结明试验、痰涂片抗酸染色阳性率相比均有显著性差异;Ⅱ、Ⅴ型结核发生率有明显差异。结论AIDS患者合并结核病发病率高,尤其以肺外结核和血型播散性结核多见,CD4 T淋巴细胞计数低于100/mm3时,临床表现不典型,胸部影象学表现多样化及结核菌素试验、结核抗体试验、痰涂片抗酸染色阳性率低。Objective To investigate the correlation between clinical features of AIDS with tuberculosis and CD4T lymphocyte count through retrospective analysis of the case of AIDS with tuberculosis. Methods the CD4T lymphocyte count of 95 cases AIDS with tuberculosis and 30 cases pure pulmonary tuberculosis were respectively detected and comparatively analyzed.. The correlation among PPD, MycoDot, TB typing and CD4T lymphocyte count in AIDS with tuberculosis cases were analyzed. Results The comparison of the level of...

关 键 词：AIDS 结核 临床分析 CD4 T淋巴细胞计数 

分 类 号：R512.91[医药卫生—内科学]