海洋真菌Aspergillus flavipes中新神经胺成分(英文)  

New cerebroside analogues from marine fungus Aspergillus flavipes

作　　者：蒋亭[1] 李军[1] 付宏征[1] 季宇彬[2] 林文翰[1] 

机构地区：[1]北京大学天然药物及仿生药物国家重点实验室,北京100083 [2]哈尔滨商业大学药物研究所博士后科研工作站,黑龙江哈尔滨150076

出　　处：《哈尔滨商业大学学报（自然科学版）》2002年第6期597-602,共6页Journal of Harbin University of Commerce：Natural Sciences Edition

基　　金：国家自然科学基金 (No 40 1760 3 8)

摘　　要：从黄海葵Anthopleuraxanthogtammica(Berkly)中分离出海洋附生真菌Aspergillusflavipes ,经实验室培养和化学分离纯化 ,分离得到四种新颖结构的神经酰胺同系物 (1— 4 ) ,它们的化学结构经波谱解析 (1R、UV、2DNMR、MS等 )From the mycelium of the marine fungus Aspergillus flavipes ,isolated from its associated anemona Anthopleura xanthogtammica (Berkly),four new cerebroside analogues,namely (4E,8E) 1 O (β D glucopyranosyl) 2 (2' hydroxyheptadecanoylamideo) 3 hydroxyl 9 methyl 4,8 nonadecadiene 1,(4E,8E) 1 O (β D glucopyranosyl) 2 (2' hydroxyl (E) 3' heptadecenoylamideo) 3 hydroxyl 9 methyl 4,8 nonadecadiene 2;(4E,8E)-1-O-(β-D-galacpyranosyl)-2-(2'-hydroxy heptadecanoylamideo)-3-hydroxyl-9-methyl-4,8-nonadecadiene 3,(4E,8E)-1-O-(β-D-galacpyranosyl)-2-(2'-hydroxyl-(E)-3'-heptadecenoy-(amideo)-3-hydrocyl-9-methyl-4,8-nonadecadiene) 4 are isolated,their structures are identified by means of extensive spectroscopic analysis,(IR,UV,2D NMR,MS,et al)and chemical degradation.

关 键 词：真菌 神经酰胺 结构确定 

分 类 号：R917[医药卫生—药物分析学]