Chemical Constituents from Roots of Semiaquilegia adoxoides  

天葵子的化学成分研究(英文)

作　　者：牛锋[1] 谢光波[1] 崔征[2] 陈发奎[2] 屠鹏飞[1] 

机构地区：[1]北京大学药学院天然药物学系,北京100083 [2]沈阳药科大学中药学院生药教研室,辽宁沈阳110016

出　　处：《Journal of Chinese Pharmaceutical Sciences》2006年第4期251-254,共4页中国药学（英文版）

基　　金：Ministry of Science and Technology of People'sRepublic of China (No. 2004AA2Z3730)

摘　　要：Semiaquilegia adoxoides ( DC. ) Makino ( Chinese name ''Tian-Kui-Zi'' ) , theonly species of genus Semiaquilegia, belongs to the Ranunculaceae family. As a perennial herbaceousplant, both the aerial parts and the roots are used in traditional Chinese medicine for differentmedications. The roots are often used to treat inflammation, snake bite, bruises and injuries,tonsillitis, mastitis, scrofula, and cancer for their antibacterial, anti-inflammatory, andantineoplastic activities. The aerial parts are used for the treatment of mastitis, bruises, andheart diseases, such as endomyocarditis. The medicinal usage of this plant prompted us toinvestigate its chemical constituents. As a result, nine compounds 1-9 ( see Figure 1) were isolatedfrom the roots of S. adoxoides. Among them, compounds 1-7 and 9 were isolated from the genusSemiaquilegia for the first time.目的研究天葵子Semiaquilegia adoxoides的化学成分。方法采用多种色谱方法分离化学成分,依据理化性质、波谱数据分析进行结构鉴定。结果分离鉴定了9个化合物,分别为:邻苯二甲酸-二-2-乙基-己酯(1),对苯二甲酸-二丁酯(2),富马酸(3),3-羟基-4-羟基苯甲酸(4),阿魏酸(5),辛二酸(6),5-(2-羟乙基)-2-O-β-D-吡喃葡萄糖基苯酚(7),4-[β-D-芹糖-(1→6)-O-β-D-吡喃葡萄糖基]苯乙腈(8),芬氏唐松草定碱(9)。结论化合物1 -7和9为首次从天葵属中分离得到。

关 键 词：Semiaquilegia adoxoides chemical constituents structure determination 

分 类 号：R284[医药卫生—中药学]