多囊卵巢综合征患者血清瘦素水平测定的意义  

Serum leptin concentrations in women with polycystic ovary syndrome

作　　者：田红革[1] 

机构地区：[1]胜利石油管理局中心医院,山东东营257034

出　　处：《山东医药》2002年第31期3-4,共1页Shandong Medical Journal

摘　　要：为了探讨多囊卵巢综合征(PCOS)患者血清瘦素(Leptin)水平测定的临床意义,选择47例PCOS患者与34例体重相匹配的对照妇女,于卵泡期测定Leptin、体重指数(BMI)、腰围(WC)、腰臀比(WHR)、胰岛素(INS)、内分泌激素,并对其进行相关与回归分析。结果:PCOS组血清Leptin浓度(18.69±8.05)ng/ml,对照组(17.09±10.35)ng/ml,差异无显著性(P>0.05);PCOS组血清INS浓度(12.45±8.07)mU/L,对照组(5.95±1.19)mU/L,差异有显著性(P<0.01)。Leptin与BMI、WC、WHR、INS成正相关。认为PCOS患者血清Leptin水平并不高于对照组,Leptin水平与体脂分布、INS有关,可能间接参与PCOS的病变形成。To study the serum leptin changes in PCOS,forty-seven subjects with PCOS and thirty-four bodymass index-matched control subjects were recruited from infertility clinics. Body mass index(BMI),waist to hipraio (WHR), waist circumference (WC), serum Insulin and leptin concentrations were assessed in all thesesubjects. All baseline evaluations were carried out in the early follicular phase of the menstrual cycle. The resultsshowed serum leptin concentrations were not different in subjects with PCOS and controls...

关 键 词：多囊卵巢综合征 瘦素 体重指数 胰岛素 

分 类 号：R711.75[医药卫生—妇产科学]