超临界CO_2萃取红车轴草异黄酮的工艺研究  

Study on Extraction of Isflavones from Trifolium pratense by Supercritical CO_2

作　　者：金汝城[1] 赵国磊[2] 贾超[2] 谢伟雪[2] 

机构地区：[1]兰州理工大学生命科学与工程学院,甘肃730050 [2]兰州理工大学石油化工学院,甘肃730050

出　　处：《中国现代应用药学》2008年第z1期625-628,共4页Chinese Journal of Modern Applied Pharmacy

摘　　要：目的采用超临界CO2萃取技术对红车轴草异黄酮成分进行萃取。通过单因素试验对影响异黄酮提取率的工艺因素进行了探讨,得出最佳的超临界萃取工艺条件为:原料粒度40目,无水乙醇做夹带剂,相对于原料用量为1 mL.g-1,萃取温度40℃,压力25 MPa,CO2流量6 mL.min-1,静态萃取60 min,动态萃取15 min。OBJECTIVE Extraction technology of isflavones in Trifolium pratense was studied by employ methods of supercritical CO2 extraction(SFE).Effects on extraction rate of isflavones were investigated by single factor experiment.The optimum extraction conditions for Trifolium pratense isflavones were established as follows: the granule size material at 40 mu,ethanol Absolute as modifier,ratio of modifier to material 1 mL·g-1,extraction temperature 40 ℃,extraction pressure 25 Mpa,CO2 flow rate of 1 mL·min-1,static extraction time 60 min,dynamic extraction time 15 min.

关 键 词：超临界CO2萃取 红车轴草 异黄酮 

分 类 号：R284.2[医药卫生—中药学]