门静脉动脉化对肝硬化犬肝切除后肝功能的影响  

Study of the effect of portal vein arterialization on the changes of liver function in hepatocirrhosis after partial hepatectomy

作　　者：王鹏[1] 李鹏[1] 李厚祥[1] 

机构地区：[1]南通大学附属医院普外科,南通226001

出　　处：《南通大学学报（医学版）》2008年第6期453-455,共3页Journal of Nantong University(Medical sciences)

摘　　要：目的:了解门静脉动脉化(Portal vein arterialization,PVA)对肝硬化犬肝切除后肝功能的影响。方法:随机分为3组:A组(动脉化组):行肝左外叶切除加门静脉动脉化手术;B组(对照组):仅行肝左外叶切除手术;C组(假手术组);每组均于术后4周处死,实验过程中检测肝功能谷草转氨酶(AST)、血浆总蛋白(TP)、血清总胆素红素(TBIL)。结果:术后AST值A组较B组明显降低(P<0.01);TP值A组大于B、C组(P<0.05);TBIL值A组下降快于B组(P<0.01)。结论:门静脉动脉化能改善肝硬化犬部分肝切除后的肝功能。Objective:To study the effect of portal vein arterialization(PVA)on the changs of liver function in hepatocirrhosis after party hepatectomy in dogs.Methods:The liver cirrhosis model of dogs was set up.The dogs were divided into three groups randomly,group A(PVA group):partial hepatectomy(42%)plus PVA were given;group B(control group):only partial hepatectomy(42%)was given;group C(sham-operated group).All dogs were killed at four weeks after operations.During the experiment,changes in liver function(AST,TP,T...

关 键 词：门静脉动脉化 肝硬化 肝功能 犬 

分 类 号：R657.3[医药卫生—外科学]