脱氢枞酸的结构修饰及生物活性研究进展  

Research progress in structural modification and biologic activities of dehydroabietic acid

作　　者：王玉民[1,2] 赵振东[1] 毕良武[1] 李冬梅[1] 

机构地区：[1]中国林业科学研究院林产化学工业研究所,国家林业局林产化学工程重点开放性实验室,江苏南京210042 [2]泰山医学院化学与化学工程学院,山东泰安271016

出　　处：《现代化工》2008年第S2期328-330,332,共4页Modern Chemical Industry

基　　金：国家自然科学基金资助项目(30571466);国家“十一五”科技支撑项目(2007BAD82B01)

摘　　要：对脱氢枞酸进行进一步的结构修饰,以获得生物活性更强、活性谱更广的衍生物是林产化工近几年的热点领域之一。根据去氢枞酸的结构特点,分别从脂环上取代基的结构修饰及生物活性、脂环的结构修饰及生物活性、脂环和取代基的共修饰及生物活性3个不同的侧面,较系统地综述了近几年来脱氢枞酸结构修饰及其生物活性的研究进展。Structural modification is still a popular and important route in the sylvo-chemical field for finding novel dehydroabietic acid derivatives with more potential bio-activities and broad bio-active spectra.According to the structural characteristics,the recent advances and research progress in the structural modification of dehydroabietic acid and biologic activities of these derivatives are focused and reviewed by three kinds of structural modifications,which were carried out to substituents linked on alicy...

关 键 词：脱氢枞酸 生物活性 结构修饰 

分 类 号：O621.2[理学—有机化学]