骨的显微损伤及其对骨力学性能的影响  

Bone microdamage and associated bone mechanical properties

作　　者：宋国路[1] 于志锋[1] 汤亭亭[1] 裘世静[2] 

机构地区：[1]上海交通大学医学院附属第九人民医院骨科 [2]美国亨利福特医院骨矿研究室

出　　处：《医用生物力学》2008年第6期486-489,共4页Journal of Medical Biomechanics

摘　　要：骨的显微损伤是由于反复受载所致的仅能在显微镜下观察到的骨基质的损伤,往往表现为各种形态的显微裂纹或弥散性损伤。通过特殊染色和标记可对显微损伤进行组织学观察和定量分析,并根据其形态和与骨单位的位置关系进行分类。显微损伤往往伴有骨强度的降低和骨脆性的增加,裂纹的长度及其位置是影响骨力学性能的决定因素。显微损伤的积累最终会导致骨的疲劳骨折。Bone microdamage usually appearing in different type of microcracks in the bone matrix as a result of repetitive mechanical loading and can only be identified by microscopy.Histologic observation and quantitative analysis could be done based on the specific staining and labeling.The microdamage could be classified by their morphology and position related to the osteon.Bone microdamage is often accompanied with the decrease of bone strength and the increase of bone fragility.The length and location of the mi...

关 键 词：骨 显微损伤 骨单位 骨强度 骨脆性 

分 类 号：R683.2[医药卫生—骨科学]