经皮冠状动脉腔内成形术对急性心肌梗死患者左室重构及心功能的影响  

Effect of percutaneous transluminal coronary angioplasty on left ventricular remodeling and function in patients with acute myocardial infarction

作　　者：刘伶[1] 王风[1] 林英忠[1] 赵毅兰[2] 徐广马[1] 林虹[1] 

机构地区：[1]广西壮族自治区人民医院心血管内科,广西南宁530021 [2]广西壮族自治区人民医院超声科,广西南宁530021

出　　处：《中国现代医学杂志》2008年第21期3217-3219,3222,共4页China Journal of Modern Medicine

摘　　要：目的探讨经皮冠状动脉腔内成形术(PTCA)对急性心肌梗死(AMI)患者左室重构及心功能的影响。方法61例首次AMI患者按发病到达医院时间不同随机分两组,6h内为A组共30例行急诊PTCA,6h后为B组共31例行延迟PTCA。两组均于术后3d、1个月、3个月行心脏彩超检查,测定左心功能各项指标:测定左室舒张末容积(LVEDV)、左室收缩末容积(LVESV)、左室射血分数(LVEF),并进行比较分析。结果PTCA术后3d、1个月和3个月,A组LVEDV、LVESV和LVEF均显著优于B组(P<0.05、P<0.05和P<0.05)。A组1个月时与3d比,LVEDV及LVESV显著缩小(P<0.05和P<0.05),LVEF显著增加(P<0.05);3个月时与1个月比LVEDV、LVESV、LVEF仍有改善,但差异无显著性。B组1个月时与3d比,LVEDV、LVESV和LVEF有改善,但差异无统计学意义;3个月时与3d比,LVEDV、LVESV明显降低(P<0.05),LVEF有改善,但差异无显著性。结论急诊PTCA能挽救濒死心肌,抑制左室重塑,改善左心功能,其效果优于延迟PTCA,延迟PTCA虽不能显著改善左心功能,但可抑制左心室重塑。Objective To explore the effect of percutaneous transluminal coronary angioplasty(PTCA) on lately left ventricular remodeling and function in patients with acute myocardial infarction.MethodsSixty one patients with acute myocardial infarction were randomly classified into 2 groups accoding to the time of arriving at the hospital.Group A(n =30) was performed emergency PTCA in 6 hours.Group B(n =31) was performed delayed PTCA after 6 hours.Left ventricular diastolic volume(LVEDV), left ventricular systolic vo...

关 键 词：急性心肌梗死 经皮冠状动脉腔内成形术 超声心动描记 左室功能 

分 类 号：R542.22[医药卫生—心血管疾病]