大黄促进人体小肠溶菌酶分泌的临床研究  

Correlation between rhubarb and the secretion of lysozyme in small intestine of human

作　　者：黄建贤[1] 黎惠娟[1] 陈少玲[1] 黄林[1] 陈晓理[2] 

机构地区：[1]广东深圳市宝安区人民医院外一科,广东深圳518101 [2]四川华西医院,四川成都610014

出　　处：《中国现代医学杂志》2008年第24期3659-3661,共3页China Journal of Modern Medicine

摘　　要：目的观察大黄对肠道溶菌酶分泌的影响。方法将80个患有胃肠道肿瘤的病人随机分为两组,实验组给患者在术前2d晚间1次,术前1d早,晚各1次共3次,每次口服10%大黄液100mL,对照组相应服用饮用水。所有患者均应在距曲氏韧带80～100cm的范围内用肠钳限制10cm长度的肠段用细针穿刺肠管注入生理盐水10mL,轻揉肠管后回收液体。立即冷冻保存。分别测定两组溶液中溶菌酶的含量。结果大黄口服灌洗液中的溶菌酶的含量与饮用水相比明显增高(P<0.01)。两者之间的差异有统计学意义。结论大黄促进人体小肠溶菌酶的分泌,这是大黄保护、增强肠道黏膜的作用机制之一。[Objective] To separate Lysozyme from small intestine of human and observe the effect of Rhubarb on the secretion of Lysozyme in small Intestine.[Method] 80 case were divided randomizedly into two groups:Experimental group were given with 100 mL 10% Rhubarb decoction two day before operation;In Control group,normal water instead of Rhubarb decoction.All cases,injected salt-water 10 mL and callback in the intestine at the 80~100 cm form treize ligament..Lysozyme activity and content were assayed by Bacterici...

关 键 词：溶菌酶 肠道屏障 细菌移位 大黄 

分 类 号：R285.5[医药卫生—中药学]