注射用清开灵冻干粉抗炎及免疫调节作用研究  

Experimental Studies on the anti-inflammatory and immune effects of Qingkailing Freeze-Dried Powder for Injection(QKLFDPI)

作　　者：李莉[1] 李东[1] 黄继华[1] 肖华[1] 古曦[1] 杨芳炬[1] 

机构地区：[1]四川大学华西基础医学与法医学院药理室,成都610041

出　　处：《中药药理与临床》2008年第5期59-60,共2页Pharmacology and Clinics of Chinese Materia Medica

摘　　要：目的:研究注射用清开灵冻干粉抗炎及免疫调节作用。方法:采用二甲苯致小鼠耳肿胀模型及角叉菜胶致大鼠足肿胀模型观察清开灵冻干粉抗炎作用。采用小鼠腹腔巨噬细胞吞噬实验观察清开灵冻干粉免疫调节作用。结果:注射用清开灵冻干粉能显著减轻二甲苯所致小鼠耳廓肿胀并且有效对抗角叉菜胶所致大鼠足肿胀,显著增强巨噬细胞吞噬能力。结论:注射用清开灵冻干粉具有显著的抗炎和免疫增强作用。Objective: To study the anti-inflammatory and immune effects of Qingkailing freeze-dried powder for injection(QKLFDPI).Methods: The anti-inflammatory effects were observed with models of xylene-induced mouse ear swelling and carrageen-induced rat paw edema.The immune effects was investigated with the phagocytotic test of intraperitoned macrophages in mice.Results: QKLFDPI can obviously inhibit the mouses ear swelling induced by xylene and suppress the rats paw edema elicited by carrageenan.It can also enha...

关 键 词：清开灵冻干粉 抗炎 免疫 

分 类 号：R285[医药卫生—中药学]