中成药所致肾脏损害12例临床分析  

Clinical features of nephropathy due to traditional herb drugs:a report of 12 cases

作　　者：宋岩[1] 姚凤华[1] 李学义[1] 张壹言[1] 陈凤锟[1] 李冀军[1] 殷培[1] 

机构地区：[1]解放军总医院第一附属医院肾内科,北京100037

出　　处：《感染．炎症．修复》2008年第4期230-231,共2页Infection Inflammation Repair

摘　　要：目的:探讨中成药所致肾脏损害的临床特点。方法:回顾分析12例服用中成药龙胆泻肝丸及冠心苏合丸所致马兜铃酸肾病患者的临床及病理资料,分析其临床及病理特点。结果:12例均为中老年患者,临床表现为慢性小管间质性肾病,伴有不同程度的肾功能损害,临床以夜尿增多、乏力及纳差等发病。病理以寡细胞性肾间质灶状或弥漫性纤维化为特征。结论:对中老年合并肾损害的冠心病患者及临床表现为慢性小管间质性肾病患者应注意询问有无龙胆泻肝丸及冠心苏合丸用药史,以防漏诊及误诊。Objective:To investigate the clinical characteristics of renal injury induced by traditionat Chinese medicine.Methods:Twelve patients with coronary disease or abdominal distention were treated with traditional Chinese medicine Longdan Xiegan pill(龙胆泻肝丸)and Guangxin Suhe pill(冠心苏合丸)for 6—96 months,and then they were diagnosed as suffering from aristolochic acid nephropathy.Their clinical and pathological data were analyzed retrospectively.Results:All the 12 patients were middle-aged or elderly.All of them we...

关 键 词：龙胆泻肝丸 冠心苏合丸 马兜铃酸肾病 慢性小管间质性肾病 

分 类 号：R285[医药卫生—中药学]