辛基酚、壬基酚联合毒作用对雄性大鼠精子影响的实验研究  

Experimental study of octylphenol,nonylphenol joint toxic effect on the sperm of male rats

作　　者：陆璐[1] 杨晓燕[1] 李晖[1] 

机构地区：[1]新疆医科大学公共卫生学院劳动卫生与环境卫生学教研室,新疆乌鲁木齐830011

出　　处：《新疆医科大学学报》2008年第12期1659-1660,1663,共3页Journal of Xinjiang Medical University

摘　　要：目的:观察辛基酚、壬基酚联合染毒时,对雄性大鼠精子状况的影响。方法:将雄性大鼠90只,随机分为9组,隔天染毒,连续60d,取出大鼠附睾,做精子的精子数、活动度以及畸形率的检测。结果:辛基酚、壬基酚对大鼠的精子数,精子活动度,精子畸形率不仅存在单独效应(P<0.05),还存在交互效应(P<0.05)。使精子数的数量和活动度降低,畸形率升高。结论:辛基酚和壬基酚联合染毒对大鼠的精子具有明显的损伤作用。Objective:To investigate the influences of the sperm of male rats impact,when octyl phenol,nonylphenol joint exposured.Methods:Ninety male rats were randomly devided into nine groups.SD male rats were daily administrated by gavage for 60 days.remove the rat epididymis to detect sperm.Result:Octylphenol,nonylphenol on rat sperm number of sperm activity,sperm abnormality rate not only had separate effect(P<0.05).They also exist interaction effect(P<0.05).The sperm quantity and the activity reduced,and i...

关 键 词：雄性大鼠 联合染毒 精子 

分 类 号：R114[医药卫生—卫生毒理学]