老年人产超广谱β-内酰胺酶细菌医院获得性肺炎的危险因素分析  

Analysis on Risk Factors of Nosocomial Pneumonia by Extended-spectrum β-lactamases-producing Bacteria in Elder

作　　者：徐卫[1] 石娜[1] 薛利霞[1] 舒雪芹[1] 廖洪菊[1] 金嵘[1] 

机构地区：[1]温州医学院附属第一医院,浙江温州325000

出　　处：《浙江预防医学》2009年第1期15-17,58,共4页Zhejiang Journal of Preventive Medicine

摘　　要：目的对老年人产超广谱β-内酰胺酶(ESBLs)大肠埃希菌和肺炎克雷伯菌医院获得性肺炎的危险因素进行探讨,以便积极采取有效的预防措施。方法收集2003-2006年的41例ESBLs阳性大肠埃希菌和肺炎克雷伯菌医院获得性肺炎老年病例,同时选取60例ESBLs阴性大肠埃希菌和肺炎克雷伯菌医院获得性肺炎老年病例为对照。对两组患者的危险因素进行病例对照研究,采用多因素非条件Logistic回归分析。结果多因素非条件Logistic回归分析表明,患有肾病(OR=26.272,95%CI为1.940～355.733)、使用三代头孢菌素(OR=9.187,95%CI为2.110～39.997)、动静脉置管(OR=7.714,95%CI为2.123～28.022)、使用氟喹诺酮类抗菌药物(OR=5.524,95%CI为1.417～21.534)、使用抗酸剂(OR=3.609,95%CI为1.054～12.360)和使用激素(OR=3.464,95%CI为1.051～11.412)是老年人产ESBLs细菌医院获得性肺炎的独立危险因素。结论应根据危险因素采取有效措施来减少老年患者中ESBLs细菌的感染。Objective To explore the risk factors of nosocomial pneumonia by extended-spectrum β-lactamases-producing bacteria in elder and formulate effective preventive measures.Methods 41 elder cases with nosocomial pneumonia by positive-escherichia coli(ESBLs) and klebsiella pneumonia were collected as case group from 2003 to 2006,and 60 controls with nosocomial pneumonia by negative-escherichia coli(ESBLs) and klebsiella pneumonia were collected as control group.Multivariate unconditional logistic regression analy...

关 键 词：超广谱Β-内酰胺酶 医院获得性肺炎 危险因素 

分 类 号：R563.1[医药卫生—呼吸系统]