本草养颜膏对老龄大鼠皮肤SOD和Hyp的影响  

On the Influence of Herbaceous Beauty Parlor Cream on the SOD and Hyp of Old Rat's Skin

作　　者：王萍[1] 王小燕 

机构地区：[1]甘肃中医学院医学美容教研室,甘肃兰州730000 [2]甘肃省静宁县中医院,甘肃静宁743400

出　　处：《中医药学报》2009年第1期18-20,0,共4页Acta Chinese Medicine and Pharmacology

基　　金：甘肃省中医药科研项目;编号:06-GZK-34

摘　　要：目的:研究本草养颜膏对老龄大鼠皮肤组织中超氧化物歧化酶(SOD)活性及羟脯氨酸(Hyp)含量的影响。方法:将SPF级SD雌性老龄大鼠50只随机分为5组:阳性对照组、模型对照组和本草养颜膏治疗高、中、低剂量组,每组10只;另取SPF级SD雌性青龄大鼠10只,作为空白对照组。分别给予维生素E、本草养颜膏基质及高、中、低剂量的本草养颜膏,于第2疗程(20天)和第3疗程(30天)结束时以生化分析法测定皮肤组织中SOD活性和Hyp含量。结果:至第3疗程结束时,本草养颜膏高、中、低剂量组均能明显提高老龄大鼠皮肤组织中SOD活性(P<0.01)和Hyp含量(P<0.01),尤其以中剂量组为最佳。结论:本草养颜膏对大鼠皮肤衰老具有延缓的作用。其机制可能是通过提高皮肤中SOD活性及Hyp含量,增强机体抗氧化和清除自由基以及合成胶原蛋白的能力,来达到延缓皮肤衰老的作用。Objective:The article aims at studying the influence of SOD active and Hyp contents in Herbaceous Beauty Parlor Cream on old rats skin.Methods:Fifty old female rats of SPF level were divided into five groups randomly.They are the positive group,model group,the high,moderate and low dosage groups of Herbaceous Beauty Parlor Cream.There were ten rats in each group.And we also took ten young female rats of SPF level as contracting group.The groups were provided with Vitamin E,the basic substance of Herbaceous ...

关 键 词：本草养颜膏 皮肤 SOD HYP 实验研究 

分 类 号：R285.5[医药卫生—中药学]