电针足三里穴对胃运动的影响及其与中缝大核的关系  

Relationship between the effect of electroacupuncturing znsanli point on gastric motility and nucleus raphes magnus

作　　者：骆豆豆[1] 杨雪娟[1] 安书成[1] 

机构地区：[1]陕西师范大学生命科学学院,陕西西安710062

出　　处：《陕西师范大学学报（自然科学版）》2009年第1期60-64,共5页Journal of Shaanxi Normal University：Natural Science Edition

基　　金：陕西省自然科学基金资助项目(2003C137)

摘　　要：实验采用中缝大核(NRM)内微量注射、胃内压记录、针刺调节胃运动变化等方法,研究NRM相关神经递质、受体及细胞因子与电针影响大鼠胃运动之间的关系.结果显示,电针显著抑制胃收缩幅度,对胃收缩频率无影响.NRM内分别注入5-HT和IL-6均能加强针刺对胃收缩幅度的抑制效应.NRM内注入纳洛酮可反转针刺效应.NRM内注射L-NAME能加强针刺抑制胃收缩幅度的效应,而NRM内注射L-Arg则可减弱或反转针刺效应.结果表明,电针足三里穴可明显抑制胃收缩幅度,针刺效应可能是通过NRM中阿片肽实现的,并通过NO调节针刺效应.NRM中的5-HT及IL-6可影响针刺对胃收缩幅度的调节作用,神经、内分泌、免疫调节系统共同参与了针刺作用.To explore the relationship between the effect of electroacupuncture on gastric motility and the neurotransmitter、receptor and cell factor of nucleus raphes magnus(NRM),the following method has been carried out.Microinjection of drugs into NRM,the frequency and the amplitude of contractions of gastric motility were recorded.The results showed that electroacupuncture at "Zusanli" point in rats could cause inhibitory effect on the amplitude of the contractions of gastric motility.But there was no obvious chan...

关 键 词：针刺 足三里穴 胃收缩幅度 中缝大核 

分 类 号：R245[医药卫生—针灸推拿学]