渗漉法和回流法提取丹参药渣中脂溶性成分的比较研究  

Study on Extraction of Liposoluble Constituents from Herb Residue of Salvia miltiorrhiza

作　　者：韩晓珂[1] 刘汉清[1] 张明[1] 马俊华[2] 马继[2] 

机构地区：[1]南京中医药大学,江苏南京210046 [2]山东华信制药有限公司,山东菏泽274009

出　　处：《现代中药研究与实践》2009年第1期61-63,共3页Research and Practice on Chinese Medicines

摘　　要：目的探讨水提后丹参药渣脂溶性成分的提取方法及其最佳工艺条件,为丹参药材的综合利用提供依据。方法以丹参酮ⅡA的含量为指标,采用正交设计优选最佳提取工艺,并进行对比、验证。结果渗漉法的最佳工艺为乙醇浓度为95%,乙醇用量为16倍,流速为1mL/min,药材目数为20目,含量高达3.279mg/g。回流法的最佳工艺为:95%乙醇,乙醇用量为10倍量,提取时间为1.5h,含量高达3.216mg/g。结论丹参酮ⅡA提取含量高,渗漉和回流两种提取方法无明显差异,丹参的综合利用完全可行。Objective In order to develop comprehensive utilization of Salvia miltiorrhiza to investigate the extraction technology of the liposoluble components from its herb residue.Methods With tanshinone Ⅱ A as index, adopting orthogonal design to optimize the extraction process.Results The optimal conditions of percolation extraction were namely using drug powder of 20 meshes added alcohol 95% of 16 fold amount with the flow rate of 1.0mL/min.The optimal refluxing was, added alcohol 95% of 10 fold amount and extra...

关 键 词：丹参 丹参酮ⅡA 回流提取法 渗漉法 

分 类 号：TQ461[化学工程—制药化工]