低能量Q开关Nd:YAG激光器和调Q开关紫翠宝石激光器治疗黄褐斑的疗效和安全性  

Efficacy and Safety of Low-energy QS Nd:YAG and QS Alexandrite Laser for Melasma

作　　者：王宏伟[1] 刘克英[1] 

机构地区：[1]中国医学科学院北京协和医学院北京协和医院皮肤科,北京100730

出　　处：《中国医学科学院学报》2009年第1期45-47,共3页Acta Academiae Medicinae Sinicae

摘　　要：目的评估低能量Q开关Nd∶YAG激光器和调Q开关紫翠宝石激光器治疗黄褐斑的疗效和安全性。方法采用低能量Q开关Nd∶YAG激光器和调Q开关紫翠宝石激光器治疗32例黄褐斑患者,以色素消退≥90%为痊愈,色素消退60%~89%为显效,色素消退30%~59%为有效,色素消退<30%为无效。结果32例患者中,21例(65.6%)痊愈,11例(34.4%)显效,痊愈患者平均治疗(10.2±3.5)次(4~15次),显效患者平均治疗(11.4±2.5)次(10~14次)。淡褐色黄褐斑患者的痊愈率和显效率分别为81.3%和18.7%,深褐色黄褐斑患者分别为50.0%和50.0%,两组相比差异有显著性(P<0.05)。病程小于2年患者的痊愈率和显效率分别为87.5%和12.5%,病程大于2年患者分别为58.3%和41.7%,两者相比差异也有显著性(P<0.05)。所有患者均未见色素加重和疤痕,仅1例出现暂时性色素脱失。结论低能量Q开关Nd∶YAG激光器和调Q开关紫翠宝石激光器可安全有效地治疗黄褐斑,黄褐斑的颜色和病程是疗效的影响因素。Objective To assess the efficacy and safety of low-energy QS Nd:YAG and QS alexandrite laser for melsasma.Methods We treated 32 patients with melasma using the low-energy QS Nd:YAG and QS alexandrite laser.Pigment subsided by ≥90% was regarded as "cured",by 60%-89% as "remarkably improved",by 30%-59% as "effective",and by<30% as "ineffective".Results Among the 32 patients,21 patients(65.6%) were cured after(10.2±3.5)times(range: 4-15 times) of treatments,11 patients(34.4%)were remarkably improved after(1...

关 键 词：低能量Q开关Nd∶YAG激光器 调Q开关紫翠宝石激光器 黄褐斑 疗效 安全性 

分 类 号：R758.42[医药卫生—皮肤病学与性病学]