洪灾区钩端螺旋体宿主动物及健康人群感染情况的流行病学研究  

Epidemiological study on leptospirosa infection of host animals and healthy population in flood areas

作　　者：周价[1] 黄昕[1] 何华先 张潇[1] 刘爱忠[1] 杨土保[1] 李硕颀[1] 汤学民[1] 谭红专[1] 

机构地区：[1]中南大学公共卫生学院,长沙410008 [2]岳阳市疾病预防控制中心,湖南岳阳414000

出　　处：《中南大学学报（医学版）》2009年第2期99-103,共5页Journal of Central South University ：Medical Science

基　　金：美国中华医学基金会项目(CMB98-689)~~

摘　　要：目的:了解洪灾区钩端螺旋体宿主动物的带菌情况及人群的免疫水平。方法:应用柯素夫培养法作牛尿和鼠肾钩体培养。显微凝集试验(microscopic agglutination test,MAT)作钩体及人群钩体感染的血清学分群(型)。结果:灾区、临灾区及新建移民点的鼠密度分别为6.95%,6.28%及8.67%;鼠肾钩体培养阳性率分别为4.63%,1.35%和3.13%;牛尿培养阳性率分别为5.88%,5.98%和1.75%;分离的菌株主要为黄疸出血型及犬型;人群钩体抗体阳性率分别为45.91%,62.30%和58.67%,明显高于全省及全国的平均感染率;其主要血清学分型依次为黄疸出血、秋季热、犬型、泼摩那型、巴达维亚型;人群抗体阳性率无年龄差异。结论:3个不同区域的宿主动物鼠和牛中均有钩体带菌,人群钩体隐性感染率水平较高,宿主动物和人群感染的主要血清群相吻合,主要为黄疸出血型。Objective To investigate the infection of leptospirosa of host animals and the immune level of healthy population in flood areas.Methods Korth culture was used to culture leptospira for rodent kidney and oxen urine sample.The serogroups of leptospira and leptospira antibody were tested by microscopic agglutination test(MAT).Results In flood regions,draw-near-flood region,and new migration region,rodent density was 6.95%,6.28%,and 8.67%,respectively.The positive rates of rodent with leptospira was 4.63%,1.35...

关 键 词：洪灾 钩端螺旋体 血清型 人群感染 宿主动物 

分 类 号：R514.4[医药卫生—内科学]