超声引导下肾囊内注射甲基强的松龙治疗肾小球肾炎  

Ultrasound-guided renal intracapsular injection of methylprednisolone for primary glomerulonephritis

作　　者：胡琳[1] 周平[1] 周鹏[1] 田双明[1] 李兴华[1] 王利华[1] 张浩[2] 

机构地区：[1]中南大学湘雅三医院超声科,长沙410013 [2]中南大学湘雅三医院肾内科,长沙410013

出　　处：《中南大学学报（医学版）》2009年第3期264-268,共5页Journal of Central South University ：Medical Science

摘　　要：目的:探讨超声引导下肾脂肪囊内注射甲基强的松龙治疗原发性肾小球肾炎的临床价值。方法:对30例原发性肾小球肾炎的患者在超声引导下行肾脂肪囊内甲基强的松龙注射,注药前后分别测定其24h尿蛋白、血清总蛋白、血清白蛋白、尿量、血清肌酐。计算肾脂肪囊注药的成功率,比较注药前后各项检验指标有无变化。结果:肾脂肪囊厚度≥5mm者成功率96.3%(314/326);肾脂肪囊厚度<5mm者成功率77.4%(212/274),两者比较差异有统计学意义(P<0.01)。穿刺并发症主要有穿刺部位疼痛、肾周血肿等。注药后24h尿蛋白定量有明显下降(P<0.05);而血清总蛋白、白蛋白均有明显升高(P<0.05);尿量、血清肌酐无明显变化(P>0.05)。结论:超声引导下肾脂肪囊内注射甲基强的松龙成功率高,疗效好,是糖皮质激素治疗原发性肾小球肾炎的一种有效的用药方法。Objective To evaluate ultrasound-guided renal intracapsular injection of methylprednisolone for primary glomerulonephritis.Methods Thirty patients with primary glomerulonephritis were performed intra-renal adipose capsule injection therapy under ultrasound guidance.The 24 hour urinary protein,plasma total protein,plasma albumin,urine volume,and serum creatinine were measured before and after the treatment.Results The injection success rate was 96.3%(314/326) in patients whose width of perinephric adipose ca...

关 键 词：介入性超声 肾脂肪囊 原发性肾小球肾炎 甲基强的松龙 

分 类 号：R692.3[医药卫生—泌尿科学]